Re: so tired of life..
You sound quite depressed if I'm honest, have you been to see your doctor? It may be that you have S.A.D?
The friends - sod them, if they've ditched you and ignore you then why would you even want to know them? Surely you deserve better than that?
The Acne - again visit your doctor and he/she will be able to give you different options on how this can be managed. If it's something that bothers you so much why are you putting off treatment?
The weight gain - start exercising. It doesn't have to be anything vigorous. A 15 minute run two/three times a week is adequate. Start eating healthily and drinking plenty of water/juice. This in turn may even help to clear up some of the acne.
You have a good job, you're intelligent and you have so much to look forward to in life. Try to see beyond what you are going through right now.
Here is a dua that is very helpful when you are feeling down - "O Allah, when I lose hope because my plans have come to nothing, then help me to remember that your love is always greater than my disappointments and your plans for my life are always better than my dreams.." (Ameen)