Nanomaterials in drug delivery and cancer

Science & Technology Science & Nature
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**
Role of nanomaterails in Drug Delivery and Cancer treatment**

               ( A Joint University-Industry Workshop, July 28-29, 2008 )

**Introduction:
**
The unique chemical and physical properties of nanomaterials are stimulating joint ventures in academia, industry and government across the globe to explore their applications. Beyond new uses in electronics, optics, and catalysis, nanomaterials hold promise in the discovery and delivery of new drugs to combat various diseases including cancer. Research in this area is progressing from bench to clinic and, in a few cases, to commercialization.

This workshop will draw participants from industry, academia and government who will discuss advances and future challenges in this rapidly growing field, and propose ways in how it can stimulate joint university-industry research in Pakistan.

Venue: PICIC Auditorium (First Floor, Main Academic Block) ,Lahore,Pakistan

Programme:

Day 1 (July 28, 2008)
(Moderated by Hassna R. Ramay)

09:00 - 09:30 : Registration/seating

09:30 - 09:40 : Welcome and introduction to the SSE and the workshop
**(Professor Asad A. Abidi, Dean, LUMS SSE)
**

09:40 - 10:25 : An overview of nanotechnology research in Pakistan
**(Dr.N.M. Butt, Chairman, Pakistan Science Foundation (PSF) and National Commission on NanoScience & Technology (NCST)) **

10:25 - 10:45 :Refreshments

10:45 - 11:30 :Keynote Lecture: Nano-probing of cancer: Simulations and experiments in understanding tumor invasion and metastasis
(M. Hamid Zaman, University of Texas at Austin, USA/LUMS SSE)

11:30 - 12:15 :From molecule to market: Pharmaceutical drug development and the role of innovative drug delivery systems
(**Qasim Iftikhar, Clinical Development Consultant London, UK)
**

12:15 - 13:00 : Gold nanoparticles: Synthesis and applications in drug delivery and cancer treatment
**(Irshad Hussain, LUMS SSE)

**
13:00 - 14:00 :Lunch break

14:00 - 14:45 :Role of biopolymeric nanomaterials in drug delivery
(M. Saeed Iqbal, Professor and Chairperson, Dept. of Chemistry, GCU, Lahore)

14:45 - 15:30 :Identification and management of hereditary breast cancer patients in Pakistan
(M. Usman Rashid, Shaukat Khanum Memorial Cancer Hospital & Research Centre, Lahore)

15:30 - 16:15 : Optimization of techniques to predict response to nepadjuvnat chemotherapy in locally advanced breast cancer using tc-99m scintimammography
(Aleem Khan, NORI, Islamabad)

16:15 - 16:30 :Refreshments

16:30 - 17:45 :Panel discussion

17:45 - 18:15 : Short contributory talks

20:00 - 21:30 : Dinner

Day 2 (July 29, 2008)
(Moderated by Tayyaba Asim)

09:30 - 10:15 : The forgotten world of colloids: Self-organizing nanostructures
(Khalid Rasheed, LUMS SSE)

10:15 - 11:00 : Super-paramagnetism and nanoparticles: Biomedical applications
(Falak Sher, PIEAS, Islamabad)

11:00 - 11:15: Tea/Coffee break

11:15 - 12:00 : Nanoparticle MRI
(Muhammad Sabieh Anwar, LUMS SSE)

12:00 - 12:45 : Nanomaterials for tissue regeneration
(Hassna R. Ramay, LUMS SSE)

12:45 - 14:00 : Lunch break

14:00 - 14:45 :The potential role of nanomaterials in drug target identification and delivery of anti-viral and anti-cancer agents
(Mazhar Iqbal, NIBGE, Faisalabad)

14:45 - 15:30 :Synthesis of steroids by palladium-mediated cascade cyclization
(Abdul Rauf Raza Chaudhary, Dept. of Chemistry, University of Sargodha)

15:30 - 16:15 : Design synthesis and characterization of protein nanopores
(M. Raza Shah, HEJ Research Institute of Chemistry, Karachi)

16:15 - 16:20 : Refreshments

16:30 - 17:15 :Structural and mechanistic aspects of platinum anti-cancer agents
(Saeed Ahmad, Dept. of Chemistry, UET, Lahore)

17:15 - 18:00 : Stimuli responsive switchable polymeric micro/nano structures: Applications towards next generation health care
(Nasir M. Ahmad, NUST, Rawalpindi)

18:00 - 18:10 :Recommendations and vote of thanks
**(M. Hamid Zaman, University of Texas at Austin, USA/LUMS SSE) **

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Re: Nanomaterials in drug delivery and cancer

Principal organizer:

Irshad Hussain, PhD
LUMS SSE
[email protected]

Co-organizers:

M. Hamid Zaman, PhD
University of Texas, USA & LUMS SSE
[email protected]

Bilal Zuberi, PhD
GEO2 Technologies Inc., USA
[email protected]
**

Organizing secretary:**

M. Sabieh Anwar, PhD
LUMS SSE
[email protected]

Treasurer:

Sarah Mahmood
[email protected]

**
Local arrangements:**

SSE Project Team

*Sonsored by:
*
1. HEC,Government of Pakistan

  1. Noor

  2. Rays Technologies

  3. Analytical Measuring Systems,Pvt Ltd.

  4. Ayub Brothers

  5. Eco Biosciences

  6. H.A Shah and Sons

  7. Webrolhers

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Re: Nanomaterials in drug delivery and cancer

About the Organizers : Hamid Zaman is an Asst. Prof. in the Departments of Biomedical Engineering and Cell and Molecular Biology and member of Institute of Theoretical Chemistry as well as Institute for Computational Engineering and Sciences and of Center for Synthetic and Systems Biology at UT Austin. He obtained his PhD from the Chemistry Department at the University of Chicago, focusing on the protein folding, dynamics and interactions. His current research focuses on developing interdisciplinary tools to study interaction of cells with extra-cellular matrices, particularly in cancer progression and metastasis. He has developed new techniques, both theoretically and experimentally to study this problem. Hamid has and continues to publish extensively in highly prestigious international journals. His research has been recognized broadly through various international awards. In 2007, he was awarded the FEBS (Federation of European Biochemical Societies) Young Investigator Award in Matrix Biology, an award rarely given to anyone outside the European Union. Recently, he was also named International Visiting Fellow at the University of Sydney, Australia. His work on cell migration in 3D, published in the Proceedings of the National Academy of Sciences, was hailed world-wide as one of the major breakthroughs in cancer in 2006. Prior to his position at UT Austin, Hamid was Hermann and Margaret Sokol Foundation Post-Doctoral Fellow at MIT and was a Burroughs Wellcome Foundation Graduate Fellow at the University of Chicago during his Ph.D. During his undergraduate, Hamid was also the awarded Alfred Crabaugh Outstanding Senior Award, given to the best undergraduate student at the entire University. More information about Hamid’s work at UT Austin is available at zlabs.bme.utexas.edu.

Timepass -April 2012
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Re: Nanomaterials in drug delivery and cancer

Irshad Hussain: Irshad Hussain received PhD degree from The University of Liverpool, UK, in 2005 on the synthesis of metal nanoparticles and their subsequent use as building blocks to design and fabricate new materials such as porous metals, nanocompsoites, nanochains and polyelectrolyte-metal nanoparticle films etc. Before his PhD, he has been working at National Institute for Biotechnology and Genetic Engineering (NIBGE), Faisalabad, to workout biotechnological solutions to various environmental problems. He had also worked in the group of Professor Dr. Atta-ur-Rehman and Professor Dr. M. Iqbal Chaudhary at HEJ Research Institute of Chemistry (HEJRIC) during 1994-95, immediately after his MSc from Quaid-i-Azam University, Islamabad.Dr. Hussain is the pioneer to develop nanobiotech research in Pakistan and has already established a nanobiotech group at NIBGE to develop the synthesis of metal nanoparticles and explore their applications in biotechnology and advanced materials fabrication. He has published several research articles in prominent journals including Nature Materials, Advanced Materials, Journal of the American Chemical Society, Small, ChemCommun and Langmuir etc. He has delivered several lectures at national and international forums to highlight the potentials of nanotechnology in various disciplines with particular reference to his own research achievements in this emerging field. His current research interests include synthesis and applications of metal/semi-conductor nanoparticles/quantum dots in disease diagnostics and treatment, catalysis and new materials fabrication. In 2007, Dr. Hussain was awarded a Professor Atta-ur-Rehman Gold Medal/Prize in chemistry to acknowledge his achievements in this field during the last five years. Current impact factor of Dr. Hussain is 82 with a citation of over 200. On-going research: In addition to his current assignments at LUMS SSE, Dr. Hussain is also guiding his previous nanobiotech research group at NIBGE on the synthesis of metal nanoparticles and to explore their applications in PCR diagnostics, fingerprinting, gene delivery and catalysis etc.

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Re: Nanomaterials in drug delivery and cancer

Bilal Zuberi: Dr. Bilal Zuberi has received his Ph.D. in Physical Chemistry from the Massachusetts Institute of Technology(MIT). Dr. Zuberi's thesis work, funded by NASA and AFSOR, was completed under the guidance of Prof. Mario J. Molina (1995 Nobel Laureate - Chemistry). His research focuses on the microphysics of aerosols, heterogeneous atmospheric chemistry in urban environments, and the fate of organic and inorganic particulate species in the atmosphere. Dr. Zuberi has worked at The Boston Consulting Group in the intellectual property strategy and industrial goods practice areas, and is a co-founder and Director of Technical Business Development at GEO2 Technologies, a technology startup developing advanced ceramic materials for emissions reduction from gasoline and diesel automobiles. Dr. Zuberi has several publications in peer-reviewed journals and has presented his work at conferences and invited talks. Dr. Zuberi has been involved in higher education issues for several years, co-authored a proposal for higher education reforms in Pakistan along with US expatriate academics and professionals, and has consulted to the Higher Education Commission in Pakistan.

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Muhammad Sabieh Anwar: Muhammad Sabieh Anwar completed his D.Phil. from the Department of Physics, Oxford University (UK) in 2004, where he studied as a Rhodes Scholar from Pakistan. His dissertation was titled, Quantum Information Processing using Para-Hydrogen NMR and revolved around the preparation of pure quantum states for quantum computing. This work also constituted the world's first demonstration of quantum entanglement in the liquid state. His post-doctoral experience at the University of California, Berkeley (USA) involved the demonstration of hyperpolarized NMR using heterogeneous catalytic systems, microfluidic and lab-on-a-chip NMR, synthesis of precise magnetic fields for ex-situ NMR, algorithmic cooling, polarization lifetime studies and hypersensitive nanoparticle MRI. Prior to his doctoral studies, Sabieh received his B.Sc. (Honours) degree in electrical engineering (electronics and communications) from the UET, Lahore.Beside that he is the youngest Doctarate of Lums faculty and youngest PhD advisor of Pakistan from HEC. Sabieh's current research interests include quantum control, spin mechanisms in nanomagnetic materials and nanotechnology. His research has been published in the Physical Review Letters, A and B, Chemical Physics Letters, Analytical Chemistry, Journal of the American Chemical Society, Angewandte Chemie, Magnetic Resonance in Chemistry, Daltons Transactions and Modern Physics Letters B. He has also taught at the Punjab University, UET (Lahore), National Centre for Physics ,Quada-i-Azam University (Islamabad) COMSATS Department of Physics (Islamabad) and has been an active speaker at many national and international physics / chemistry forums.Dr. Sabieh is also the Joint Secretary and one of the founders of the Khwarzimic Science Society .a non-profit organization aiming at developing a science culture in Lahore's educational institutions. This Association has organized about 150 events of different kinds with the objective of strengthening the popular image of the scientific content and method.

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:hmmm: so DL is banned rite now :hehe:

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Re: Nanomaterials in drug delivery and cancer

Sarah Mahmood :Manager, Development: Sarah did her Masters in Mass Communications and Bachelors in Journalism and Psychology, both from Kinnaird College. She has worked at WWF (World Wide Fund for Nature) and Asiatic. She has also taught at the Lahore Grammar School. She joined the LUMS Science and Engineering Initiative Team initially as the Assistant Project Coordinator in 2004, but has since been promoted to the new role of development manager.