So true.
Also, it just might be because of the cancer diagnoses and death she's been dealing with.
To know your dad might die soon, and then it'll be on you and you are single and all alone and having to manage the load of a family.
It's pretty nerve wrecking, and not something, fortunately, a lot of girls have to go through. But those of us who are single and managing the prospect of eventually handling parents and siblings on our own shoulders while we're alone emotionally, is fairly consuming.
I can relate a lot to her, but what can you do?
Just be there for her as a friend. It always helps to have friends. And if you know some nice guys, introduce her around. Help her out, if finding a partner is going to make her happy.
Is there something else going on that you don't know about? Because there are only two things I can think of:
Besides the whole stressful rishta process, perhaps she's experienced something else...some type of emotional trauma that is doing a number on her outlook on life and her self confidence. If that is the case, then you can only be there for her...support her, listen to her, occasionally force her out of the house for some fun and distraction, and encourage her to open up to you. Ultimately, whether or not she decides to get help for whatever problem she might have is totally up to her.
After years of the crazy and oftentimes demoralizing rishta process, it's just REALLY getting to her. For women who get married later in life (and by later, I mean the desi definition of later which is late 20s, early 30s), years and years of the rishta process and unfortunately, rejection, can badly impact your self esteem. Years of "oh your daughter isn't fair enough, or educated enough or slim enough, or this enough, blah blah blah blah" would make even a supermodel with a degree in astrophysics doubt her self worth. Heck, some people don't even bother calling back much less provide a really low-class excuse.
I've seen it happen to a lot of girls, including me. It is not at all unusual. The suggestions I would offer you are pretty much the same as #1 above. Be there for her. And encourage her to keep an open mind and continue meeting with potential rishtas...it won't be easy of course. There will probably be more rejections on both sides. But Inshallah, whoever Allah has in mind for her WILL come. But only at that exact moment that Allah has decreed. No earlier, no later. That's how it worked for me (and a lot of other girls), and I couldn't be happier.
Good luck to you and your friend.