Is this end of a life long friendship?

FP,

Additional responsibilities (marriage, kids, and work) can bring about a distance between friends. It's normal and it happens. We get so wrapped up in life's chores that we don't have the time to socialize like we used to. Don't jump to conclusions about your friend yet. Maybe he's busy, or maybe his wife is controlling. It seems like you really care about your friend so why don't you be the bigger person and call him up and casually express your concerns. Just tell him, "Dude, we've had a strong friendship for years and I'm worried about you because in the past you maintained communication in spite of your responsibilities and now you seem oddly distant. If you need any help, you know where to find me." And if he has some problems in his personal life that are causing this distance, maybe he'll feel encouraged to share them with you.

^So just call him up....and if he does not want to maintain ties, then let him go. You can't force him to be your friend and try to move on with your life. If he values this friendship as much as you do, he knows how to reach you. Just continue moving on.