It depends on what it is.
If he lied about smoking…I dont think that is a deal breaker. If he lied about having dated someone in the past…not a deal breaker because its the past and hiding it is understandable in our desi culture.
Now, if he lied about his education…he doesnt really have a degree. I would worry. If he lied about children he has…I would worry. If he lied about a previous marriage…I would worry.
It depends on the weight of the situation.