Most families do have a history of illness in their family, heart disease, breast cancer genes
I think its a matter of why you are marrying the person, if u are out to get the "perfect" healthy mate...they dont exist... its only now that people esp pakistanis are becoming aware of family history in illnesses and things...
presence of abnormal/mutated/ diseased genes or traits in anyone does'nt guaranty illness or abnormality , no one is 100% sure about his own genes that whether they're r all healthy and normal , neither do U nor do I . Genes and traits could be dominent and disease becomes obvious but traits could also be recessive (hidden) and never make u sick -or- they could even become apperent later on in 2nd or may be 3rd generation. who knows better than Allah , it's nothing but a mystry called genetics . this shouldn't hamper yr decision of marrying someone who's all perfect otherwise .
Also khuda na khuasta what if u yrself ( even me) get suffered at hands of an unintentional accident or natural disaster at some point in life ??
I can't comment on a personal level, but I would have to agree with Iconoclast here. I'm aware of a case where the rishta was cancelled because of a family disease.
He was upfront about it from the start, for which I am thankful for. The side effects he had were not as bad as he scared me into thinking they’d be It’s not a secret, but it’s not an issue to discuss either.. its like… having black hair, its there, it happened, where’s the discussion in it?
On the other hand, my parents say diabetes just “disappears”..
depends on the disease, the prevalance in the family. if it's something scary like MS or something...i'm not goin in that family, or sending anyone in that family. but if it's something like heart disease...which can be worked out...i see no harm.
I was once faced with the situation where the girl's mother and Khala (Mother's sister) had debilitating ALS (Amyotropic Lateral Sclerosis) where the mother was only able to talk and move her shoulders a bit. Rest of her body was paralyzed. Her sister (girl's Khala) dies of respiratory failure. So there was no doubt that it is in their family.
We didn't konw it. We came to know from another acquaintance before even we could contact them back after visiting their home. My mom told me and I said, I don't think anybody should be judged like this. There are many ways a genetic disease can still show incomplete pnetrance, may not express for so many reasons. Only Allah knows if it is gonna get into the family or the girl has it in her genes. So we proceded but it didn't work out for some reason....
The best thing, I'd say, marry outside the family. According to Hardy weinberg's law, if random mating continues in a large population, the frequency of any genetic diseas remain constant......
H-d principle's just theoretical...it's not very practical...but i know what you mean. marriage outside of the family is the best course of action. i know a family that had been marrying in family for quite a few generations, and their kids now are displaying some very odd physical features and traits.
^ Ashkanazi Jews, who marry within their race i.e. non-random mating withing a small population have very high incidence of Ulcerative colitis, Dermatitis herpetiformis lesions and so many more. why H-D principal is not practical?
no no. that’s not what i’m talking about uff…i’m not saying h-d is completely wrong…i’m saying that it’s ideal. like ideal gases. it’s applicable in a very few cases. other factors then work in beyond those few cases. urgghh i can’t explain unless i have a textbook in my hands
and i am in no way contradicting the fact that inter-familial marriages lead to loads of genetic anamolies. Jews overall do have a higher rate of genetic health problems (one is very prominent and i just can’t seem to remember the name of it), because of the whole marrying into the same populations for eons.
5% cases of Parkinsons and Alzheimers are hereditary, res are sporadi, as i said having a first degree relative increases the likelihood of getting these but in that case you probably not find any family without a disease that makes the first degree relatives genetically susceptible, and these are quite common, like diabetes, breast cancer, colon cancer, heart failure and hundreds of others.