Not quite a pick up line but back in the engineering university in Karachi, whenever I used to see a simple looking girl student, I use to say this to my friend out loud. ‘Yaar tum tou kehtay thay NED main koi khoobsoorat larki nahi hai’.
See, oon ko koi compliment nahi deta thaa, koi seeti nahi martaa thaa oon ke liye. That was my way of boosting their esteem. 