I dont know anything about dog fights or fighters in general, but what I do know is that the F22 has a ability to target and destroy an incoming fighter well before the opposing fighter even knows whats going on... That alone seems to do the trick for US. Besides that, the US has more bombers then India can shake a stick at.
The point of posting this was not to say India can take on the US but:
If India does so well against the US, it would be foolish to think PAF will have supremacy over IAF
Indian pilots got training and exposure to fighting F-15s and F-16s. PAF pilots have no similar training on fighting Su30 mki, etc.