Re: Reduction of microalbuminuria in type-II diabetics:
Well, it is a well known fact that angiotensin receptor blockers (ARBs) like Losartan, Valsartan are effective in reducing microalbuminuria IF the ACE Inhibitors like Captopril, Analapril and lisinopril are not tolerated. The ARBs can retard the development OR the progress of not only Diabetic nephropathy but also non-diabetic nephropathy.......... again Calcium Channel Blockers cannot do in the later situation.
What I still don't understand is why calcium channel blockers are compared in this way as to my knowledge, they are not effective in effecting microalbuminuria (not to my knowledge)....... unless the creatinin clearance is a concern and patient already has a CI to ARBs?????